Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Having -c- – wherein x is chalcogen – bonded directly to...
Patent
1992-10-26
1993-07-13
Ramsuer, Robert W.
Drug, bio-affecting and body treating compositions
Designated organic active ingredient containing
Having -c-, wherein x is chalcogen, bonded directly to...
514451, 514456, 514460, 514468, 514469, 514470, 549 13, 549 23, 549 28, 549273, 549299, A61K 31365, A61K 3138, C07D30792, C07D40712
Patent
active
052273997
ABSTRACT:
Compounds having the formula I: ##STR1## are inhibitors of leukotriene biosynthesis. These compounds are useful as anti-asthmatic, anti-allergic, anti-inflammatory, and cytoprotective agents. They are also useful in treating angina, cerebral spasm, glomerular nephritis, hepatitis, endotoxemia, uveitis and allograft rejection and in preventing the formation of atherosclerotic plaques.
REFERENCES:
patent: 4486445 (1984-12-01), Patel et al.
patent: 4937373 (1990-06-01), Carson et al.
Ducharme Yves
Gillard John W.
Girard Yves
Hutchinson John H.
Nicoll-Griffith Deborah A.
DiPrima Joseph F.
Lopez Gabriel
Merck Frosst Canada Inc.
Ramsuer Robert W.
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