Organic compounds -- part of the class 532-570 series – Organic compounds – Heterocyclic carbon compounds containing a hetero ring...
Patent
1992-10-26
1994-01-25
Bond, Robert T.
Organic compounds -- part of the class 532-570 series
Organic compounds
Heterocyclic carbon compounds containing a hetero ring...
549 28, 549417, 549426, 549427, 549428, 546205, 546206, 546239, 544239, 544172, A61K 3135, C07D30930, C07D30906, C07D31194
Patent
active
052817202
ABSTRACT:
Compounds having the formula I: ##STR1## are inhibitors of leukotriene biosynthesis. These compounds are useful as anti-asthmatic, anti-allergic, anti-inflammatory, and cytoprotective agents. They are also useful in treating angina, cerebral spasm, glomerular nephritis, hepatitis, endotoxemia, uveitis and allograft rejection and in preventing the formation of atherosclerotic plaques.
REFERENCES:
patent: 4486445 (1984-12-01), Patel et al.
patent: 4937373 (1990-06-01), Carson
Ducharme Yves
Gillard John W.
Girard Yves
Hutchinson John H.
Nicoll-Griffith Deborah A.
Bond Robert T.
Daniel Mark R.
DiPrima Joseph F.
Merck Frosst Canada Inc.
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