Pyranosyl cytosines: pharmaceutical formulations and methods

Details Pyranosyl cytosines: pharmaceutical formulations and methods Pyranosyl cytosines: pharmaceutical formulations and methods

2005-08-23

2005-08-23

McKenzie, Thomas C. (Department: 1624)

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Carbohydrate doai

C536S028500, C536S028520, C536S028400, C544S317000

Reexamination Certificate

active

06933288

ABSTRACT:
This invention is directed to novel pyranosyl cytosine compounds depicted graphically as structure I. This invention is further directed to a unique methodology for their preparation using solid-phase methodology. These hexopyranosyl cytosine derived natural product analogs share their parent compounds broad-spectrum antimicrobial and anti-fungal profile and represent a vast, novel compound class of 50S rRNA directed inhibitors of protein translation.

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