Purine nucleotide antiveral composition and methods of use

Drug – bio-affecting and body treating compositions – Conjugate or complex of monoclonal or polyclonal antibody,... – Conjugated via claimed linking group – bond – chelating agent,...

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195 28N, 195 80R, 536 27, 536 28, A61K 3152, C07C 1920

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active

041361750

ABSTRACT:
The nucleotide derivatives of certain 2,6 substituted purines have been discovered to have anti-viral activity. Novel compounds and their pharmaceutically acceptable salts, pharmaceutical formulations containing the compounds of this invention, and the treatment of viral infections with these formulations are all disclosed. 2,6 Diamino-9-(.beta.-D arabinofuranosyl)-purine-5'-phosphate is an example of a more active compound of this invention.

REFERENCES:
patent: 3300478 (1967-01-01), Wechter
patent: 3328389 (1967-06-01), Shimizu et al.
patent: 3337530 (1967-08-01), Hanze
patent: 3382232 (1968-05-01), Honjo et al.
patent: 3448098 (1969-06-01), Gaines et al.
patent: 3666856 (1972-05-01), Elion et al.
patent: 3703507 (1972-11-01), Haskell et al.

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