Purine nucleoside modifications by palladium catalyzed methods

Details Purine nucleoside modifications by palladium catalyzed methods Purine nucleoside modifications by palladium catalyzed methods

1994-12-01

1996-12-03

Wilson, James O.

Organic compounds -- part of the class 532-570 series

Organic compounds

Carbohydrates or derivatives

536 276, 536 278, 536 2781, C07H 1900, C07H 1916

Patent

active

055809723

ABSTRACT:
This invention discloses an improved method for the preparation modified purine nucleosides at the 2-, 6-, or 8-position of the purine ring, using a palladium catalyst.

REFERENCES:
patent: 5047519 (1991-09-01), Hobbs, Jr. et al.
patent: 5053499 (1991-10-01), Kojima et al.
patent: 5428149 (1995-06-01), Eaton
Crisp et al., Tetrahedron Letters, vol. 31, No. 9, pp. 1347-1350, (1990).
Chemical Abstracts, vol. 115, No. 9, Sentemov et al., Abstract No. :92415h (1991).
Dewey et al., J. Am. Chem. Soc., vol. 117, No. 32, pp. 8474-8475, (1995).
Arai and Daves, Jr. (1978) J. Am. Chem. Soc. 100:287.
Bergstrom et al. (1981) J. Org. Chem. 46:1432.
Bergstrom and Ruth (1976) J. Am. Chem. Soc. 98:1587.
Bergstrom et al. (1982) J. Org. Chem. 47:2174.
Crisp (1989) Syn. Commun. 19:2117.
Dreyer and Dervan (1985) Proc. Natl. Acad. Sci. USA 82:968.
Guschlbauer et al. (1977) Nucleic Acids Res. 4:1933.
Hobbs et al. (1973) Biochemistry 12:5138.
Hacksell and Daves, Jr. (1983) J. Org. Chem. 48:2870.
Ikehara and Tada (1968) in Synthetic Procedures in Nucleic Acid Chemistry, Zorbach, W. W.; Tipson, R. S. Eds.; John Wiley and Sons, NY; p. 189.
Pieken et al. (1991) Science 253:314.
Ruth and Bergstrom (1978) J. Org. Chem. 43:2870.
Sagi et al. (1994) J. Med. Chem. 37:1307.
Sessler et al. (1993) J. Am. Chem. Soc. 115:10418.
Shibahara et al. (1987) Nucliec Acids Res. 15:4403.
Sproat et al. (1989) Nucleic Acids Res. 17:3373.
Tronchet et al. (1988) Nucleosides & Nucleotides, 7:249.
Tuerk and Gold (1990) Science 249:505.
Van Aerschot et al. (1993) J. Med. Chem. 36:2938.

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