Purine nucleoside 5'-phosphate (mono, di or tri) 3'(2')-diphosph

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C12D 1306

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040594874

ABSTRACT:
New purine nucleoside 5'-phosphate (mono, di or tri) 3'(2')-diphosphates and the sodium, lithium and potassium salts thereof are elaborated by the enzymatic transfer of pyrophosphoryl group from ATP (adenosine triphosphate), dATP (deoxyadenosine triphosphate) and pppApp (adenosine 5'-triphosphate 3'(2')diphosphate) to specified 5'-purine nucleotides, and a new nucleotide pyrophosphotransferase used for this enzyme reaction is produced by actinomycetes and other microorganisms and recovered from the culture filtrate and mycelium by the conventional methods for recovering enzymes.

REFERENCES:
patent: 3287232 (1966-11-01), Mitsugi et al.
Journal of American Chemical Society, vol. 76, pp. 2844 & 2845 (1954).

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