Purine derivatives having antiviral activity

Details Purine derivatives having antiviral activity Purine derivatives having antiviral activity

1989-07-28

1991-10-08

Rivers, Diana

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Phosphorus containing other than solely as part of an...

544244, 544243, 548112, 556404, 558175, A61K 31675, A61K 3152, C07F 96561

Patent

active

050554581

ABSTRACT:
Compounds of formula (I) and pharmaceutically acceptable salts thereof: ##STR1## wherein R.sub.1 is hydroxy, amino, chloro or OR.sub.7 wherein

REFERENCES:
patent: 4724233 (1988-02-01), De Clercq et al.
patent: 4808716 (1989-02-01), Hol et al.
patent: 4910307 (1990-03-01), Wyatt
Prisbe, et al., J. Med. Chem., vol. 29(5), pp. 671-675 (05/86).
Duke, et al., Antiviral Research, vol. 6, pp. 299-308 (1986).
Streicher, et al., Chemica Scripta, vol. 26, pp. 179-183 (1986).
Holy, et al., Collection Czechoslosovak Chem. Commun., vol. 52(9) pp. 2775-2791 (09/87).
Watson, et al., J. Org. Chem., vol. 39(19), pp. 2911-2916 (09/74).
Bronson et al., "Nucleotide Analogues as Antiviral Agents", ed. Martin, American Chemical Society, (1989), pp. 71-87.
Holy, et al., "Nucleotide Analogues As Antiviral Agents", Martin Ed., American Chemical Society, (1989), pp. 61-71.

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