Purine derivatives and their use as bronchodilators

Drug – bio-affecting and body treating compositions – Antigen – epitope – or other immunospecific immunoeffector – Bacterium or component thereof or substance produced by said...

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544277, C07D47318

Patent

active

042410630

ABSTRACT:
New 2-substituted-6-amino-9-tetrahydropyran-2-yl purine derivatives are disclosed. They are orally active bronchodilators with relatively little cardiovascular side effects. A representative and preferred embodiment of this invention is 2-n-propoxy-9-(tetrahydropyran-2-yl)-9H-adenine.

REFERENCES:
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Marumoto et al., Chem Pharm. Bull. 23(4) 759-744 (1975).
Robins, et al., JACS 83 2574 (1961).
Schaeffer et al., JACS 81 197-201 (1959).
Kikugawa et al., Chem. Pharm. Bull. 25(7) 1811-1821 (1977).

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