Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Having -c- – wherein x is chalcogen – bonded directly to...
Patent
1985-01-28
1987-03-10
Rizzo, Nicholas S.
Drug, bio-affecting and body treating compositions
Designated organic active ingredient containing
Having -c-, wherein x is chalcogen, bonded directly to...
544276, 544277, C00D41318, A61K 3152
Patent
active
046491406
ABSTRACT:
The novel compound 6-deoxyacyclovir, which itself has antiviral activity against herpes viruses, is converted enzymatically to acyclovir by xanthine oxidase/dehydrogenase or aldehyde oxygenase.
REFERENCES:
patent: 4199574 (1980-04-01), Schaeffer
patent: 4323573 (1982-04-01), Schaeffer
patent: 4544634 (1985-10-01), Krenitsky
Schaeffer, Nature, vol. 272, No. 5654, 583 (1978).
Elion, Onc. Nat. Acad. Sci., USA, vol. 74, 5716 (1977).
Brown Donald
Burroughs Wellcome Co.
Rizzo Nicholas S.
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