Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Having -c- – wherein x is chalcogen – bonded directly to...
Patent
1985-08-22
1988-09-20
Rizzo, Nicholas S.
Drug, bio-affecting and body treating compositions
Designated organic active ingredient containing
Having -c-, wherein x is chalcogen, bonded directly to...
544276, 544277, 544261, 544264, C07D47302, A61K 3152
Patent
active
047726067
ABSTRACT:
Novel purine derivatives, particularly novel guanines and hypoxanthines, are described as agents for treating autoimmune diseases. Also novel methods of manufacture for the derivatives, pharmaceutical compositions thereof, and methods of use therefor are the invention.
REFERENCES:
Discussion at 16th Annual Graduate Student Meeting in Med. Chem. at U. of M., Ann Arbor, MI "8 Amino-9-Benzylguanine".
Bio. Chem. Pharm., 31, 163-171, (1982).
J. Am. Chem. Soc. 81, 3046-3051 (1959).
J. Het. Chem., 21, 1245-6 (1984).
Heterocycles, vol. 22, No. 8, 1984, pp. 1789-1790.
Heterocycles, vol. 22, No. 11, 1984, pp. 2439-2441.
Pinter Garry W.
Sircar Jagadish C.
Rizzo Nicholas S.
Thierstein Joan
Warner-Lambert & Company
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