Purine derivative dihydrate, drugs containing the same as...

Organic compounds -- part of the class 532-570 series – Organic compounds – Chalcogen bonded directly to ring carbon of the purine ring...

Reexamination Certificate

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C544S244000, C544S264000

Reexamination Certificate

active

06919455

ABSTRACT:
A compound represented by the following formula (I), or a salt thereof:where X is a halogen atom or a group represented by —S—(CH2)n—A, —SO—(CH2)m—B, —SO2—(CH2)m—B, —OSO2—(CH2)m—B, —OCO—(CH2)m—B or —OPO(OR)—(CH2)m—B, wherein n represents an integer of 0-4, A represents an optionally substituted aromatic hydrocarbon group or an optionally substituted heterocyclic residue having 1 to 4 hetero atoms selected from an oxygen atom, sulfur atom and nitrogen atom and having 5 to 10 ring-constituent atoms, m represents an integer of 0-4, B represents an optionally substituted alkyl group, an optionally substituted aromatic hydrocarbon group or an optionally substituted heterocyclic residue having 1 to 4 hetero atoms selected from an oxygen atom, sulfur atom and nitrogen atom and having 5 to 10 ring-constituent atoms, and R represents an optionally substituted alkyl group.

REFERENCES:
patent: 3862189 (1975-01-01), Schwender
patent: 3936454 (1976-02-01), Schwender
patent: 4012495 (1977-03-01), Schmiechen et al.
patent: 4193926 (1980-03-01), Schmiechen et al.
patent: 5124455 (1992-06-01), Lombardo
patent: 5770611 (1998-06-01), Brown
patent: 5861404 (1999-01-01), Niewöhner et al.
patent: 5948913 (1999-09-01), Yamamoto et al.
patent: 6734187 (2004-05-01), Tanaka et al.
patent: 2167353 (1996-07-01), None
patent: 1043324 (2000-10-01), None
patent: 8-231545 (1996-09-01), None
patent: 92/12961 (1992-08-01), None
patent: 93/23401 (1993-11-01), None
patent: 94/11004 (1994-05-01), None
patent: 94/12461 (1994-06-01), None
patent: 94/14742 (1994-07-01), None
patent: 95/00516 (1995-01-01), None
patent: 95/10525 (1995-04-01), None
patent: 95/18815 (1995-07-01), None
patent: 96/26209 (1996-08-01), None
patent: 96/26942 (1996-09-01), None
patent: 96/36606 (1996-11-01), None
patent: 99/24432 (1999-05-01), None
patent: 00/68231 (2000-11-01), None
First Page of JP 4-253945.
First Page of JP50-157360.
First Page of JP 6-504782.
First Page of JP 9-500376.
First Page of JP 7-504442.
Angyal, A.M. et al., “Purines as Amplifiers of the Antibiotic Activity of Phleomycin AgainstEscherichia coliB,” J. Gen. Microbiology, (1974), 85, 163-68.
Beavo, J.A., Multiple Isozymes of Cyclic Nucleotide Phosphodiesterase, Adv. Second Messenger Phosphoprotein Res., 22, 1-38 (1988).
Beavo, J.A. and Reifsnyder, D.H., Primary Sequence of Cyclic Nucleotide Phosphodiesterase Isozymes and the design of Selective Inhibitors, Trends Pharm. Sci., 11, 150-155 (1990).
Hidaka, H. and Shibuya, M., A New Assay of Cyclic Nucleotide Phosphodiesterase; its Application to Human Serum, Biochem. Med. 10, 301-311 (1974).
C.D. Nicholson, S.A. Jackman & R. Wilke, The ability of denbufylline cyclic nucleotide phosphodiesterase and its affinity for adenosine receptors and the adenosine re-uptake site, Br. J. Pharmacol, (1989), 97, 889-897.
Torphy, T.J. and Undem, B.J., Phosphodiesterase Inhibitors: New Opportunities for the Treatment of Asthma, Thorax, 46, 512-523 (1991).
Global Initiative for Chronic Obtructive Lung Disease (NIH, National Heart, Lung and Blood Institute) p. 6.
Makino et al., International Archives of Allergy and Immunology, 121(Suppliment 1) pp. 4, 5, 54, 33, 36-39(2000).
Benjamin K. Gill, “Diagram Representing the Roles of Cytokines in Inflammatory Responses” http://attila.stevens-tech.edu/chembio/bgill/IL 10K.html.

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