Purifying and isolating method for hepatitis virus to use in pre

Details Purifying and isolating method for hepatitis virus to use in pre Purifying and isolating method for hepatitis virus to use in pre

1977-03-15

1979-02-06

Rosen, Sam

Textiles: fiber preparation

424 89, C12K 700, A61K 3912

Patent

active

041382870

ABSTRACT:
Hepatitis B virus (detectable as its surface antigen HB.sub.s Ag) is produced in a purification preferably suitable for use in preparing a hepatitis vaccine, by contacting a crude biological starting material containing hepatitis B virus with a water-insoluble cross-linked sulfated polysaccharide gel matrix adsorbing agent to adsorb the hepatitis B virus thereon and then desorbing that virus therefrom by treating that hepatitis B virus carrying adsorbent with a desorbing agent.

REFERENCES:
patent: 3636191 (1972-01-01), Blumberg et al.
patent: 3925152 (1975-12-01), Porath et al.
patent: 3976767 (1976-08-01), Neurath

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