Purified vacuolating toxin from Helicobacter pylori and methods

Details Purified vacuolating toxin from Helicobacter pylori and methods Purified vacuolating toxin from Helicobacter pylori and methods

1995-06-07

2000-01-11

Housel, James C.

Chemistry: molecular biology and microbiology

Measuring or testing process involving enzymes or...

Involving antigen-antibody binding, specific binding protein...

435 732, 4242361, G01N 3353

Patent

active

060134631

ABSTRACT:
This invention relates to a purified Helicobacter pylori vacuolating toxin and methods to use this toxin to produce protective antibodies against H. pylori infection. Antiserum to this antigen can be used to detect the toxin. Methods to detect anti-toxin antibodies determine the susceptibility of a patient to develop peptic ulcer disease, gastric carcinoma, or other clinical consequences of H. pylori infection.

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