Purified transforming growth factor beta

Chemistry: natural resins or derivatives; peptides or proteins; – Proteins – i.e. – more than 100 amino acid residues – Hormones – e.g. – prolactin – thymosin – growth factors – etc.

Patent

Rate now

  [ 0.00 ] – not rated yet Voters 0   Comments 0

Details

530395, 530350, 530829, 930120, C07K 1500

Patent

active

051049775

ABSTRACT:
A composition for the promotion of cell proliferation and tissue repair in animals having as active ingredients a TGF-.beta. which is activated by either a TGF-.alpha. or an EGF or both; and methods for administration. As another embodiment these active ingredients can be admixed with other (secondary) growth factors.

REFERENCES:
patent: 4686283 (1987-08-01), Nestor et al.
patent: 4708948 (1987-11-01), Iwata et al.
patent: 4742003 (1988-05-01), Derynck et al.
patent: 4774322 (1988-09-01), Seyedin et al.
patent: 4816442 (1989-03-01), McPherson et al.
patent: 4816561 (1989-03-01), Todaro
Todaro et al, Transforming growth factors . . . epidermal growth factor receptors, P.N.A.S. 77(9), pp. 5258-5262, 1980.
Todaro et al, Growth factors produced by Sarcoma Virus-transformed cells, Cancer Res., 38, pp. 4147-4154, 1978.
Stromberg et al, Human Term Placenta Contains Transforming Growth Factors, Biochem. Biophys, Res. Comm., pp. 354-361, 1982.
Chem Abstract No. 142402j.
Anzano et al, Synergistic interaction of two classes of TGF . . . cells, Can Res 42, 1982, pp. 4776.
Sporn et al, Polypeptide TGF isolated from bovine . . . in vivo, Science 219, 1983, p. 1329.
Twardzik et al, TGF in urine . . . Tumor bearing humans, JNCI, vol. 69(4), 1982, p. 793.
Roberts et al, PNAS 77, 1980, pp. 3494-3498.
DeLarco et al, Nature, 272, 356-358 (1978).
Holley et al, Proc. Natl. Acad. Sci. U.S.A., 77, No. 10, 5989-5992 (1980).
Massague et al, The Journal of Biological Chemistry, 260, 4551-4554 (1985).
Marquardt et al, The Journal of Biological Chemistry, 255, No. 19, 9177-9181 (1980).
Marquardt et al, The Journal of Biological Chemistry, 256, No. 13, 6859-6862 (1981).
Moses et al, Oncogenes and Growth Control, Edited by P. Kahn and T. Graf, 50.56, (1986).
Anzano et al, Analytical Biochemistry, 125, 217-224 (1982).
Brown et al, Proc. Natl. Acad. Sci. U.S.A., 84, 3743-3747 (1987).
DeLarco et al, Proc. Natl. Acad. Sci. U.S.A., 75, No. 8, 4001-4005 (1978).
Kovacina et al, Biochemical and Biophysical Research Communications, vol. 160, No. 1, pp. 393-403 (1989).
Moses et al., "Tranforming Growth Factor Production by Chemically Transformed Cells", Cancer Research, 41:2842-2848 (Jul., 1981).
Tucker, et al., "Comparison of Intra- and Extracellular Transforming Growth Factors from Nontransformed . . . ", Cancer Research, 43:1581-1586 (Apr., 1983).
Moses, et al., "Transforming Growth Factor-.beta.", in "Oncogenes and Growth Control", P. Kahn and T. Graf, eds., Springer-Verlag Berlin Heidelberg, 1986.

LandOfFree

Say what you really think

Search LandOfFree.com for the USA inventors and patents. Rate them and share your experience with other people.

Rating

Purified transforming growth factor beta does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Purified transforming growth factor beta, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Purified transforming growth factor beta will most certainly appreciate the feedback.

Rate now

     

Profile ID: LFUS-PAI-O-2350566

  Search
All data on this website is collected from public sources. Our data reflects the most accurate information available at the time of publication.