Purified sperm surface antigen, monoclonal antibody therefor and

Details Purified sperm surface antigen, monoclonal antibody therefor and Purified sperm surface antigen, monoclonal antibody therefor and

1996-06-28

1998-11-03

Eisenschenk, Frank C.

Drug, bio-affecting and body treating compositions

Immunoglobulin, antiserum, antibody, or antibody fragment,...

Monoclonal antibody or fragment thereof

5303882, A61K 39395, C07K 1600

Patent

active

058304720

ABSTRACT:
The monoclonal antibody S19, expressed by Deposit HB12144, ATCC, effectively agglutinates a sperm surface glycoprotein, SAGA-1 protein. The mAB finds utility as a binding agent in a spermicide, showing a high degree of effectiveness in binding potential sperm. The protein bound, identified as SAGA-1, is the immunogen in a contraceptive vaccine, as well as the standard for determining antibody titer upon vaccination. The monoclonal antibody can also be used as a diagnostic to determine the presence, and amount, of sperm in a variety of samples.

REFERENCES:
patent: 5227160 (1993-07-01), Nudelman et al.
patent: 5605803 (1997-02-01), Herr et al.
Mahoney et al. (1991) J. Reprod. Immunol. 19:269-285.
Cone et al. (1994) Am. J. Reprod. Immunol. 32:114-131.

Affiliated with

Also associated with

Rating

Purified sperm surface antigen, monoclonal antibody therefor and does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Purified sperm surface antigen, monoclonal antibody therefor and, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Purified sperm surface antigen, monoclonal antibody therefor and will most certainly appreciate the feedback.

Rate now

Comments { 0 }

Profile ID: LFUS-PAI-O-686727