Chemistry: natural resins or derivatives; peptides or proteins; – Proteins – i.e. – more than 100 amino acid residues – Separation or purification
Patent
1985-09-20
1988-02-23
Kight, John
Chemistry: natural resins or derivatives; peptides or proteins;
Proteins, i.e., more than 100 amino acid residues
Separation or purification
530416, 530414, 530417, 530827, 530350, 514 2, 514 21, 435 7, 435 68, 435 70, 436518, 436536, 436811, 436815, C07K 328, A61K 3702, G01N 33536
Patent
active
047271370
ABSTRACT:
A substantially pure protein having angiogenic activity is disclosed. A method for preparing proteins having angiogenic activity from cell culture media is also disclosed. Proteins produced according to the invention are useful in the diagnosis of malignancies, for promoting wound healing, and for other diagnostic and therapeutic purposes.
REFERENCES:
patent: 4229531 (1979-07-01), Tolbert
patent: 4268629 (1981-05-01), Tolbert et al.
patent: 4503038 (1985-03-01), Banda et al.
patent: 4529590 (1985-07-01), La Veen et al.
Fineberg, S. E. et al., Diabetes Care, vol. 5, (Suppl. 2), pp. 107-113, 1982.
Fineberg, S. E. et al., Diabetologia, vol. 25, pp. 465-469, 1983.
Folkman et al., J. Exp. Med., vol. 133, 275-288 (1971).
Tuan et al., Biochemistry, vol. 12, 3159-3165 (1973).
McAuslan et al., Exp. Cell. Res., vol. 119, 181-190 (1979).
McAuslan, Control Mechanisms in Animal Cells (Jiminez de Asua, L., Shields, R., Levi-Montalcini, R., & Iacobello, S., eds.), pp. 285-292.
Fenselau et al., J. Biol. Chem., vol. 256, 9605-9611 (1981).
Vallee et al., Experientia, vol. 41, 1-15 (1985).
Phillips et al., Int. J. Cancer, vol. 23, 82-88 (1979).
Weiss et al., Br. J. Cancer, vol. 40, 493-496 (1979).
Kumar et al., Int. J. Cancer, vol. 32, 461-464 (1983).
Shing et al., Science, vol. 223, 1296-1299 (1984).
Banda et al., Proc. Nat'l. Acad. Sci., 79:7773-7777 (1982).
D'Amore, Proc. Nat'l. Acad. Sci. 78:3068-3072.
Fett James W.
Vallee Bert L.
Draper Garnette D.
Kight John
President and Fellows of Harvard College
LandOfFree
Purified protein having angiogenic activity and methods of prepa does not yet have a rating. At this time, there are no reviews or comments for this patent.
If you have personal experience with Purified protein having angiogenic activity and methods of prepa, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Purified protein having angiogenic activity and methods of prepa will most certainly appreciate the feedback.
Profile ID: LFUS-PAI-O-603486