Chemistry: natural resins or derivatives; peptides or proteins; – Proteins – i.e. – more than 100 amino acid residues
Patent
1989-02-15
1990-08-14
Naff, David M.
Chemistry: natural resins or derivatives; peptides or proteins;
Proteins, i.e., more than 100 amino acid residues
435 681, 435 711, 435272, 435820, 530820, 530825, C07K 1504, C07K 312, C07K 1500, C12P 2100
Patent
active
049488740
ABSTRACT:
A process is disclosed for recovering a cell wall protein, particularly a Fc-receptor, from streptococcal bacteria. In the process, streptococcal bacteria are treated with at least one proteolytic enzyme to solubilize the cell wall protein. A process is also disclosed for recovering Fc-receptor type III (protein G) having selective IgG-binding capability (i.e., no albumin-binding capability) from streptococcal bacteria by pretreating these bacteria with enzymes prior to said enzymatic solubilization.
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Bjorck et al., "Purification and Some Properties of Streptococcal Protein G, a Novel IgG Binding Reagent", J. Immunol, 133 (2) (1984), pp. 969-974.
Bjorck Lars
Kronvall Goran
Naff David M.
Pharmacia AB
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