Drug – bio-affecting and body treating compositions – Extract – body fluid – or cellular material of undetermined... – Urogenital system
Patent
1985-10-29
1991-04-30
Goldberg, Jerome D.
Drug, bio-affecting and body treating compositions
Extract, body fluid, or cellular material of undetermined...
Urogenital system
514 8, 530395, 530397, A61K 3548
Patent
active
050116878
ABSTRACT:
Purified Mullerian inhibiting substance (MIS) is obtained from testicular tissue by extraction, density gradient sedimentation and chromatography. The purified MIS has selective activity for inhibiting the growth of human ovarian cancer cells.
REFERENCES:
Hakala and Rustum, Methods in Cancer Research, XVI:247 (1979).
National Cancer Institute Monograph, 55 (1980).
Cowan and Van Hoff, Cancer Chemotherapy, 1, (1983).
Tanneberger et al., Cancer Chemotherapy and Selective Drug Development (1984).
Salmon, Human Tumor Cloning, 499-508 (1984).
Rosenwaks et al., Abstract 174, 65th Annual Meeting, The Endocrine Society, Jun. 8, 1983.
Fuller et al., Gynecologic Oncology, "Mullerian Inhibiting Substance Inhibition of a Human Endometrial Carcinoma Cell Line Xenografted in Nude Mice," 1984 (preprint).
Donahoe et al., Annals of Surgery, 194: 472-480 (Oct., 1981); Fuller, Jr. et al., Gynceologic Oncology, 17: 124-132 (1984).
Swann, D. A., Donahoe, P. K. et al., Developmental Biology, vol. 69:73 (1979).
Donahoe, P. K. et al., Biology of Reproduction, 16:238-243 (1977).
Josso, N. et al., Biology of Reproduction, 13:163-167 (1975?).
Josso, N., J. Clin. Endocrinology, 34:265-270 (1972).
Picard, J. Y., and Josso, N., Biomedicine 25:147-150 (1976).
Donahoe Patricia K.
Swann David A.
Goldberg Jerome D.
The General Hospital Corporation
LandOfFree
Purified Mullerian inhibiting substance and process for treating does not yet have a rating. At this time, there are no reviews or comments for this patent.
If you have personal experience with Purified Mullerian inhibiting substance and process for treating, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Purified Mullerian inhibiting substance and process for treating will most certainly appreciate the feedback.
Profile ID: LFUS-PAI-O-639540