Purified interleukin 2

Details Purified interleukin 2 Purified interleukin 2

1988-06-10

1990-05-15

Kight, John

Chemistry: natural resins or derivatives; peptides or proteins;

Proteins, i.e., more than 100 amino acid residues

Lymphokines, e.g., interferons, interlukins, etc.

424 852, 514 2, 514885, C07G 700

Patent

active

049259199

ABSTRACT:
Interleukin 2 (IL 2; T-cell growth factor), produced with and without costimulation by Burkitt's lymphoma line Daudi, is highly purified approximately over 37,000-fold to apparent homogeneity from lymphocyte-conditioned medium derived from normal human blood cells by (NH.sub.4).sub.2 SO.sub.4 -precipitation, ion-exchange chromatogr

REFERENCES:
patent: 4315852 (1982-02-01), Leibowitz et al.
patent: 4390623 (1983-06-01), Fabricius et al.
patent: 4401756 (1983-08-01), Gillis
patent: 4448879 (1984-05-01), Fabricius et al.
patent: 4450103 (1984-05-01), Konrad et al.
patent: 4462940 (1984-07-01), Hanisch et al.
patent: 4464295 (1984-08-01), Bhaduri et al.
patent: 4464355 (1984-08-01), Fabricius et al.
patent: 4476049 (1984-10-01), Kung
patent: 4490289 (1984-12-01), Stern et al.
patent: 4508833 (1985-04-01), Sonneborn et al.
patent: 4511502 (1985-04-01), Builder et al.
patent: 4511503 (1985-04-01), Olson et al.
patent: 4512922 (1985-04-01), Jones et al.
patent: 4518584 (1985-05-01), Mark et al.
patent: 4530787 (1985-07-01), Shaked et al.
patent: 4564593 (1986-01-01), Tsukamoto et al.
patent: 4569790 (1986-02-01), Koths et al.
patent: 4572798 (1986-02-01), Koths et al.
patent: 4675383 (1987-06-01), Bohlen et al.
patent: 4738927 (1988-04-01), Taniguchi et al.
patent: 4778879 (1988-10-01), Mertelsman et al.
patent: 4789658 (1988-12-01), Yoshimoto et al.
Watson et al., J. Exp. Med., (1979), 150:849-861.
Derynck et al., Nature, (1980), 287:193-197.
Gillis et al., J. Immunol., (1980), 124:1954-1962.
Mochizuki et al., J. Immuno. Meth., (1980), 39:185-201.
Henriksen et al., Cell Immunol., (1982), 73:106-114.
Ihle et al., J. Immunol., (1982), 129(6):2431.
Welte, K., et al., J. Exp. Med., (1982), 156:454-464.
Lymphokine Res., (1982), I(2), FASEB Editorial.
Coughlin, R. T., et al., Federation Proceedings, (1983), 42(7):2022.
Devos et al., Nucleic Acid Res., (1983), 11(13):4307.
Henderson et al., J. Immunol., (1983), 131(2):810-815.
Milstone et al., Biochem. Biophy. Res. Comm., (1983), 115(3):762-768.
Riendeau et al., J.B.C., (1983), 258(20):12114-12117.
Taniguchi et al., Nature, (1983), 302:305.
Robb, R. J. Immunology Today, (1984), 5(7):203.
Rosenburg, S. A., Science, (1984), 223:1412.
Stern, A. S., et al., Proc. Natl. Acad. Sci. (U.S.A.), (1984), 81:871-875.
Wang, Alice, et al., Science, 224:1431-1433.
"Chromatographic Removal of Pyrogens," Bio/Technology, Dec. 1984, 1035-1038.
Lahm et al., J. of Chromatography, (1985), 326:357-361.
Rosenberg et al., New England Journal of Medicine, (1985), 313:1485-1492.
Reed, S., et al., J. Immunol., vol. 133, No. 6, pp. 3333-3337, (1984).
Ruscetti, F. and Gallo, R., Blood, vol. 57, No. 3, pp. 379-394, (Mar. 1981).
Stotter, H. and Rude, E., Eur. J. Immunol., vol. 10, pp. 719-722, (1980).
Farrar, J., et al., Immunol. Rev., vol. 63, pp. 129-166, (1982).
Kawamura, H., et al., J. Exp. Medicine, vol. 162, pp. 381-386, (1985).
Mier, J. and Gallo, R., J. Immunol., vol. 128, pp. 1122-1127, (1982).

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