Purified equine immunologlobulins and method of use thereof

Details Purified equine immunologlobulins and method of use thereof Purified equine immunologlobulins and method of use thereof

1986-11-25

1990-03-27

Stone, Jacqueline M.

Drug, bio-affecting and body treating compositions

Lymphokine

424 88, 424101, 530387, 530416, C07K 1506, A61K 39395, A61K 3940, A61K 3516

Patent

active

049119109

ABSTRACT:
Equine immunoglobulins are recovered from the pass-through fraction of a QAE column loaded with equine serum in an acidic buffer. The recovered antibodies are electrophoretically free of non-immunoglobulin proteins, including transferrin, and are recovered in a higher yield than with known methods. The purified immunoglobulins may be used to treat failure of passive transfer of maternal immunity to foals.

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P. C. Montgomery, Molecular Aspects of Equine Antibodies; Proc. 3d. Int. Conf. Equine Infectious Diseases 343-363 (1973).
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Nielsen et al., cited in Biol. Abstracts 81:23731, 1986 (Feb. 1).
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