Purified DNA of the 170-kd surface Gal/GalNAc adherence lectin o

Details Purified DNA of the 170-kd surface Gal/GalNAc adherence lectin o Purified DNA of the 170-kd surface Gal/GalNAc adherence lectin o

1990-11-21

1993-11-09

Wax, Robert A.

Organic compounds -- part of the class 532-570 series

Organic compounds

Carbohydrates or derivatives

536 235, 536 231, 536 254, C07H 1700, C07H 2300

Patent

active

052604292

ABSTRACT:
cDNA encoding the 170 kd subunit of Gal/GalNAc lectin in various strains of E. histolytica is provided. Availability of this cDNA permits the use of diagnostic assays to distinguish pathogenic from nonpathogenic strains based on DNA hybridization, and further permits antisense approaches to interrupting the production of this lectin.

REFERENCES:
patent: 4683195 (1987-07-01), Mullis et al.
Tannich et al. P.N.A.S. 88:1849 (1991).
Sammelson et al. J. Clin. Microb. 27(4):671 (1989).
Mann et al. P.N.A.S. 88:3248 (1991).
Mirelman et al., Infection & Immunity (1986) 54(3):827-832.
Petri et al., J. Biol. Chem. (1989) 264(5):3007-3012.
Ravdin et al., Infection & Immunity (1986) 53(1):1-5.
Petri et al., J. Clin. Invest. (1987) 80:1238-1244.
Petri, Jr. et al., Am. J. Med. Sci. (1989) 296(7):163-165.
Root et al., Arch. Invest. Med. (Mex) (1978) 9:Supplement 1:203-210.
Palacios et al., Arch. Invest. Med. (Mex) (1978) 9:Supplement 1:339-348.
Randall et al., Trans. Roy. Soc. Trop. Med. Hyg. (1984) 78:593-595.
Grundy, Trans. Roy. Soc. Trop. Med. Hyg. (1982) 76(3):396-400.
Ungar, Am J. Trop. Med. Hyg. (1985) 34(3):465-472.
Ravdin ed., Amebiasis: Human Infection by Entamoeba Histolytica, (1988) Wiley Medical Publishing Co., pp. 661-663.
Ravdin ed., Amebiasis: Human Infection by Entamoeba Histolytica, (1988) Wiley Medical Publishing Co., pp. 646-649.
Garfinkel et al., Infection & Immunity (1989) 57:(3):926-931.
Tannich et al., Proc. Natl. Acad. Sci. (1989) 86:5118-5122.
Strachan et al., Lancet (Mar. 12, 1988) pp. 561-562.

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