Purified and isolated platelet calcium channel nucleic acids...

Chemistry: molecular biology and microbiology – Measuring or testing process involving enzymes or... – Involving antigen-antibody binding – specific binding protein...

Reexamination Certificate

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C435S007210, C435S320100, C435S325000, C536S023500

Reexamination Certificate

active

10726216

ABSTRACT:
Isolated and purified platelet voltage dependent calcium channel (VDCC) α1subunit polypeptides, and nucleic acid molecules encoding the same. Recombinant host cells, recombinant nucleic acids, and recombinant proteins are also disclosed, along with methods of producing each. Isolated and purified antibodies to platelet VDCC α1subunit polypeptides, and methods of producing the same, are also disclosed. Platelet VDCC α1subunit polypeptides have biological activity in calcium transport. Thus, therapeutic and diagnostic methods involving this activity are also disclosed.

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