Purified and isolated platelet calcium channel nucleic acids

Details Purified and isolated platelet calcium channel nucleic acids Purified and isolated platelet calcium channel nucleic acids

2006-05-09

2006-05-09

Murphy, Joseph (Department: 1646)

Chemistry: molecular biology and microbiology

Micro-organism, tissue cell culture or enzyme using process...

Recombinant dna technique included in method of making a...

C435S320100, C435S325000, C530S350000, C536S023100, C536S023500

Reexamination Certificate

active

07041475

ABSTRACT:
Isolated and purified platelet voltage dependent calcium channel (VDCC) α1subunit polypeptides, and nucleic acid molecules encoding the same. Recombinant host cells, recombinant nucleic acids and recombinant proteins are also disclosed, along with methods of producing each. Isolated and purified antibodies to platelet VDCC α1subunit polypeptides, and methods of producing the same, are also disclosed. Platelet VDCC α1subunit polypeptides have biological activity in calcium transport. Thus, therapeutic and diagnostic methods involving this activity are also disclosed.

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