Purified activin B composition

Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Peptide containing doai

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514 8, 514 21, 530399, A61K 3702, A61K 3743

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active

050718347

ABSTRACT:
A pharmaceutical composition and method are provided for erythropoietin therapy, such as treatment of an anemic disease, wherein an effective amount of activin with two beta.sub.B chains formulated in a pharmaceutically acceptable carrier is administered to a patient or animal in need of such therapy. Preferably the activin is human and the composition is administered parenterally.

REFERENCES:
patent: 4879226 (1989-11-01), Wallace et al.
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Mason et al., Biochem. Biophys. Res. Commun. 135 (3):957-964 (1986).
Mason et al., "Inhibin-Non-Steroidal Regulation of Follicle Stimulating Hormone Secretion", Serono Symposia Publications from Raven Press, vol. 42, pp. 77-88 (1987).
Eto et al., Biochem. Biophys. Res. Commun, 142 (3):1095-1103 (1987).
Murata et al., Proc. Natl. Acad. Sci. U.S.A. 85:2434-2438 (1988).
Yu et al., Nature 330:765-767 (1987).
Ikawa et al., Gann 66:583-584 (1975).
Murata et al., Biochem. Biophys. Res. Commun. 151 (1):230-235 (1988).
Mason et al., Molecular Endocrinology, 3:1352-1358 (1989).

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