Purification process of iodixanol

Organic compounds -- part of the class 532-570 series – Organic compounds – Amino nitrogen containing

Reexamination Certificate

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C570S177000, C570S178000, C570S262000

Reexamination Certificate

active

07968745

ABSTRACT:
A process for the manufacture of iodixanol by performing a purification process of the crude product in a solvent comprising n-propanol. The crude product may be obtained in aqueous solution from dimerization of 5-acetamido-N,N′-bis(2,3-dihydroxypropyl)-2,4,6-triiodo-isophthalamide (“Compound A”).

REFERENCES:
patent: 0747344 (1996-12-01), None
patent: 99/18054 (1999-04-01), None
patent: WO 9918054 (1999-04-01), None
patent: 2006/016815 (2006-02-01), None
patent: WO 2006016815 (2006-02-01), None
patent: 2007/013815 (2007-02-01), None
PCT/NO2006/000487 Int'l Search Report/Written Opinion dated Apr. 2007.

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