Purification process for manufacturing a high pure acarbose

Details Purification process for manufacturing a high pure acarbose Purification process for manufacturing a high pure acarbose

2007-08-07

2007-08-07

Jiang, Shaojia Anna (Department: 1623)

Organic compounds -- part of the class 532-570 series

Organic compounds

Carbohydrates or derivatives

C536S018700, C536S017200, C536S055300, C536S124000, C536S123100

Reexamination Certificate

active

10790069

ABSTRACT:
A process for purifying and preparing highly pure acarbose from acarbose-containing fermentation broth. The acarbose is purified through steps of alcohol precipitation, a strongly acidic cation exchanger chromatography and an immobolized enzyme affinity chromatography. Acarbose is generally applied in treating diabetes.

REFERENCES:
patent: 5989882 (1999-11-01), Crueger et al.
patent: 6649755 (2003-11-01), Hong et al.
patent: WO 99/07720 (1999-02-01), None

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