Purification process for hepatitis surface antigen and product t

Details Purification process for hepatitis surface antigen and product t Purification process for hepatitis surface antigen and product t

1984-07-09

1986-11-25

Hazel, Blondel

Chemistry: molecular biology and microbiology

Micro-organism, tissue cell culture or enzyme using process...

Enzymatic production of a protein or polypeptide

424 88, 424 89, C12P 2100, A61K 3929

Patent

active

046249184

ABSTRACT:
A method for the purification of hepatitis B surface antigen from recombinant cell culture comprising concentrating the antigen, precipitating the antigen, purifying the antigen by adsorption to an immunoaffinity column, eluting the antigen and fractionating the antigen on an anion exchange bed.

REFERENCES:
patent: 3994870 (1976-11-01), Neurath et al.
patent: 4088748 (1978-05-01), McAleer et al.
patent: 4181713 (1980-01-01), McAleer et al.
patent: 4186193 (1980-01-01), McAleer et al.
patent: 4271145 (1981-06-01), Wands et al.
patent: 4349539 (1982-09-01), Wampler
patent: 4442205 (1984-04-01), Hamer et al.

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