Purification process

Details Purification process Purification process

2006-12-12

2006-12-12

Kifle, Bruck (Department: 1624)

Organic compounds -- part of the class 532-570 series

Organic compounds

Unsubstituted hydrocarbyl chain between the ring and the -c-...

Reexamination Certificate

active

07148346

ABSTRACT:
This invention provides a process for purifying a cyclosporin, e.g. cyclosporin A, or a macrolide, to a high degree of purity on a large scale. In another aspect this invention provides a bulk quantity of cyclosporin A with an impurity level of less than about 0.7%, e.g. about 0.5%, and compositions thereof.

REFERENCES:
patent: 3244592 (1966-04-01), Aral
patent: 3503950 (1970-03-01), Li
patent: 3527750 (1970-09-01), Karr
patent: 3573275 (1971-03-01), Maehr et al.
patent: 3671647 (1972-06-01), Argoudelis et al.
patent: 3743633 (1973-07-01), Goerlich et al.
patent: 3804594 (1974-04-01), Orjans et al.
patent: 4016258 (1977-04-01), Said et al.
patent: 4081354 (1978-03-01), Christman
patent: 4203956 (1980-05-01), Schrodter et al.
patent: 4271128 (1981-06-01), Schrodter et al.
patent: 4328214 (1982-05-01), Rink et al.
patent: 4753734 (1988-06-01), Ito
patent: 4803016 (1989-02-01), Binderman et al.
patent: 4913814 (1990-04-01), Singh et al.
patent: 4954260 (1990-09-01), Ludmer et al.
patent: 5256547 (1993-10-01), Rudat et al.
patent: 5359060 (1994-10-01), Hauske
patent: 5382655 (1995-01-01), Szanya et al.
patent: 5591438 (1997-01-01), Olson et al.
patent: 5595661 (1997-01-01), Li et al.
patent: 5616595 (1997-04-01), Chu et al.
patent: 5665772 (1997-09-01), Cottens et al.
patent: 5709797 (1998-01-01), Bocchiola
patent: 6706727 (2004-03-01), Fleissner et al.
patent: 2108655 (1995-04-01), None
patent: 633 826 (1982-12-01), None
patent: 0637123 (1983-07-01), None
patent: 295 871 (1991-11-01), None
patent: 295 872 (1991-11-01), None
patent: 295 873 (1991-11-01), None
patent: 298 276 (1992-02-01), None
patent: 298 427 (1992-02-01), None
patent: 427680 (1991-05-01), None
patent: 652 219 (1993-11-01), None
patent: 652 219 (1993-11-01), None
patent: 641 861 (1995-03-01), None
patent: 652219 (1995-05-01), None
patent: 1 223 902 (1971-03-01), None
patent: 1 223 903 (1971-03-01), None
patent: 1257866 (1971-12-01), None
patent: 1 356 056 (1974-06-01), None
patent: 1 521 457 (1978-08-01), None
patent: 2 215 631 (1989-09-01), None
patent: WO 95/06059 (1995-03-01), None
patent: WO 95/11295 (1995-04-01), None
patent: 95/32726 (1995-12-01), None
patent: 96/12031 (1996-04-01), None
Wang-Fan, W.; Kusters, E.; Lohse, O.; Mark, C.-P.; Wang, Y., Journal of Chromatography, A (1999), 864(1), 69-76.
No Author, “Wikipedia, the free encyclopedia” [online]. Wikimedia Foundation Inc. St. Petersburg, FL, Feb. 6, 2006, [retrieved on Mar. 2, 2006]. Retreived from the Internet <http://en.wikipedia.org/w/index.php?title=Ascomycin&printable=yes>.
Prochazka, et al., Chem. Engineer. Science, vol. 31, pp. 179-186 (1976).
Lo and Baird, Encyc of Chem. Tech., 4thed., vol. 10, pp. 125-180, J. Wiley & Sons, 1979.
Vogel, Text book of Practical Organic Chem., Longman, 4th Edition, 1978, (pp. 211,217, 219, 220) from Experimental Techniques.

Affiliated with

Also associated with

Rating

Purification process does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Purification process, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Purification process will most certainly appreciate the feedback.

Rate now

Comments { 0 }

Profile ID: LFUS-PAI-O-3672467