Distillation: processes – separatory – With chemical reaction – Including step of adding catalyst or reacting material
Reexamination Certificate
2011-07-26
2011-07-26
Manoharan, Virginia (Department: 1771)
Distillation: processes, separatory
With chemical reaction
Including step of adding catalyst or reacting material
C203S091000, C564S497000
Reexamination Certificate
active
07985323
ABSTRACT:
Purification process for the preparation of the allylamine pharmaceutical terbinafine of formula Iin free base form or acid addition salt form, by distilling crude terbinafine base, preferably by short path distillation, e.g. at a temperature above 100° C. and reduced pressure, e.g. 0.2 mbar, and recovering the purified product in free base or acid addition salt form.
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Beutler Ulrich
Penn Gerhard
DeBenedictis Karen
Manoharan Virginia
Novartis AG
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