Purification of type G botulinum neurotoxin and pharmaceutical c

Details Purification of type G botulinum neurotoxin and pharmaceutical c Purification of type G botulinum neurotoxin and pharmaceutical c

1996-04-16

1998-12-08

Tsang, Cecilia J.

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Peptide containing doai

514 21, 530350, 530412, 530413, 530416, 530417, 530418, 530825, 435 681, 435 701, 435 703, 435842, A61K 3800, A23J 100, C12P 2104

Patent

active

058469290

ABSTRACT:
The isolation and purification of type G botulinum neurotoxin and complexes thereof is disclosed. Compositions containing the type G neurotoxin and the preparation of a type G toxoid are also disclosed.

REFERENCES:
Nukina et al, Zbl. Bakt. Hyg. A268, pp. 220-227, 1988.
Nukina et al, FEMS Microbiology Letters, vol. 79, pp. 165-170, 1991.
Girueuez et al, Zbl. Bakt. Hyg. A 262, pp. 179-188, 1986.
Ciccarelli et al, Applied Environmental Microbiology, vol. 34, No. 6, pp. 843-848, 1977.
Moberg, L.J. et al., Applied and Environmental Microbiology, vol. 35, No. 5, May 1978, pp. 878-880, "Affinity Chromatography Purification of Type A Botulinum Neurotoxin from Crystalline Toxic Complex".
Ciccarelli, A.S. et al., Applied Environmental Microbiology, vol. 34, No. 6, Dec. 1977, pp. 843-848, "Cultural and Physiological Characteristics of Clostridium botulinum Type G and the Susceptibility of Certain Animals to Its Toxin." Strain 89 of Clostridium botulinum type G, isolated by Gimenez and Ciccarelli in 1969, was characterized culturally, biochemically, and toxigenically.
Gimemez, J.A. et al., Zbl. Bakt. Hyg. A 262, (1986), pp. 179-188, "Molecular Characterization of a Protein, Insoluble at Low Temperature, Produced by Clostridium botulinum Type G".
Takeshi, K., Biol. Abstr. 83(7) AB-914, 68788 "Biochemical Properties of Clostridium botulinum Type G and Clostridium hastiforme."(1986).
Briozzo, J. et al., Applied and Environmental Microbiology, vol. 51, No. 4, Apr. 1986, pp. 844-848, "Effect of Water Activity and pH on Growth and Toxin Production by Clostridium botulinum Type G".
Nukina, M. et al., Zbl. Bakt. Hyg. A 268, 220-227 (1988), "Purification of Clostridium botulinum Type G Progenitor Toxin".
Nukina, M. et al., FEMS Microbiology Letters 79 (1991) 165-170, "Difficulties of molecular dissociation of Clostridium botulinum type G progenitor toxin".
Nukina, M. et al., FEMS Microbiology Letters 79 (1991) 159-164, "Detection of neutral sugars in purified type G botulinum progenitor toxin and the effects of some glycolytic enzymes on its molecular dissociation and oral toxicity".

Affiliated with

Also associated with

Rating

Purification of type G botulinum neurotoxin and pharmaceutical c does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Purification of type G botulinum neurotoxin and pharmaceutical c, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Purification of type G botulinum neurotoxin and pharmaceutical c will most certainly appreciate the feedback.

Rate now

Comments { 0 }

Profile ID: LFUS-PAI-O-177231