Purification of structurally ordered recombinant protein polymer

Chemistry: natural resins or derivatives; peptides or proteins; – Proteins – i.e. – more than 100 amino acid residues – Scleroproteins – e.g. – fibroin – elastin – silk – etc.

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530418, 530420, 530422, 530423, C07K 312

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active

052350410

ABSTRACT:
Recombinant structural and functional polymers are purified by lysing of the cellular host, separation of the solid materials, washing and extraction of contaminants using a detergent solution at elevated temperatures.

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patent: 4652630 (1982-03-01), Bentle et al.
patent: 4766205 (1988-08-01), Ghosh-Dashidar
Marston, Biochem. J., 240, pp. 1-12 (1986).
Kane et al., Trend-Biotech., vol. 6, pp. 95-101 (1988).
Marston et al., Biotechnology, vol. 2 pp. 799-804 (1984).

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