Chemistry: natural resins or derivatives; peptides or proteins; – Proteins – i.e. – more than 100 amino acid residues – Lymphokines – e.g. – interferons – interlukins – etc.
Patent
1986-09-04
1989-01-31
Schain, Howard E.
Chemistry: natural resins or derivatives; peptides or proteins;
Proteins, i.e., more than 100 amino acid residues
Lymphokines, e.g., interferons, interlukins, etc.
530412, 530413, 530414, 530416, 530417, 530422, 435 68, 435803, C07K 312, C07K 328
Patent
active
048016861
ABSTRACT:
A process is provided for purifying recombinant IL-1 from microbial cells, comprising suspending the cells in an aqueous buffered medium having a pH from about 1 to about 5; disrupting the cells to provide an extract containing solubilized IL-1; and recovering solubilized Il-1 from the extract.
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Draper Garnette D.
Hallquist Scott G.
Immunex Corporation
Schain Howard E.
Wight Christopher L.
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