Chemistry: natural resins or derivatives; peptides or proteins; – Proteins – i.e. – more than 100 amino acid residues – Hormones – e.g. – prolactin – thymosin – growth factors – etc.
Patent
1997-11-14
1999-12-21
Tsang, Cecilia J.
Chemistry: natural resins or derivatives; peptides or proteins;
Proteins, i.e., more than 100 amino acid residues
Hormones, e.g., prolactin, thymosin, growth factors, etc.
530324, 530350, 530412, 530416, 530417, 435 691, 435 694, 435 701, 435 711, C07K 314, C12P 2106
Patent
active
060050810
ABSTRACT:
Methods are provided for large scale purification of neurotrophins, including mature NGF, suitable for clinical use. The methods provide means to separate neurotrophins from various less desirable misprocessed, misfolded, size, glycosylated, or charge forms. Compositions of neurotrophins, including mature NGF, substantially free of these variants are also provided.
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Beck Joanne T.
Burton Louis E.
Schmelzer Charles H.
Genentech Inc.
Mohamed Abdel A.
Torchia Timothy E.
Tsang Cecilia J.
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