Chemistry: natural resins or derivatives; peptides or proteins; – Proteins – i.e. – more than 100 amino acid residues – Separation or purification
Patent
1994-11-22
1997-04-29
Sayala, Chhaya D.
Chemistry: natural resins or derivatives; peptides or proteins;
Proteins, i.e., more than 100 amino acid residues
Separation or purification
530364, 210660, 210668, 435 711, 435 712, C07K 118
Patent
active
056250410
ABSTRACT:
Problem: when proteins are purified using a protein-binding dye immobilised on a chromatographic matrix, the dye or a portion/derivative may leak into the eluant. Solution: an ion-exchange resin (e.g. Dowex-1) and a disrupting material (e.g. salt and a fatty acid such as sodium octanoate) are used to separate the dye from the protein.
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Johnson Richard A.
Quirk Alan V.
Woodrow John R.
Delta Biotechnology Limited
Moore Steven J.
Sayala Chhaya D.
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