Purification of polymorphic components of complex genomes

Chemistry: molecular biology and microbiology – Measuring or testing process involving enzymes or... – Involving nucleic acid

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536 27, 935 77, 935 78, C12Q 168, C07H 1512, C12N 1500

Patent

active

050325027

ABSTRACT:
A method is disclosed for processing related subject and reference macromolecule populations composed of complementary strands into their respective subject and reference populations of representative fragments and effectuating purification of unique polymorphic subject fragments.

REFERENCES:
patent: 4283489 (1981-08-01), Goodman et al.
patent: 4861708 (1989-08-01), Frossard
Yokota et al., Proc. Natl. Acad. Sci., U.S.A., vol. 87, pp. 6398-6402, Aug. 1990.
Roninson, Nucleic Acids Research, pp. 5413-5431 (1983).

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