Purification of pneumococcal capsular polysaccharides

Organic compounds -- part of the class 532-570 series – Organic compounds – Carbohydrates or derivatives

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424 92, 424180, 536 18, C07H 300, C08B 3700

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042425018

ABSTRACT:
A multivalent pneumococcal vaccine of the group consisting of immunogenic amounts of purified pneumococcal capsular polysaccharide (substantially absent "C" polysaccharide) of pneumococcal types (Danish designation) 1, 2, 3, 4, 6A, 6B, 7F, 8, 9N, 12F, 14, 18C, 19F, 20, 23F, and 25 and combinations thereof and methods of purifying pneumococcal capsular polysaccharide types 1, 2, 3, 4, 6A, 6B, 7F, 8, 9N, 12F, 14, 18C, 19F, 23F and 25.

REFERENCES:
Borgono, J., et al., Proc. Soc. Exp. Biol. Med., vol. 157, 148-154 (1978).
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Hilleman, M., et al., Biol. Abstracts, vol. 67, 28387 (1979.
Cowan, M., et al., Chem. Abstracts, vol. 90, 20714x (1979).
Glaudemans, C., et al., Carbohyd. Res., vol. 4, 181-184, (1967).
Williams, C., et al., Methods in Immunology and Immunochemistry, vol. I, 52-60, Academic Press, New York, 1967.

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