Chemistry of inorganic compounds – Treating mixture to obtain metal containing compound – Radioactive metal
Reexamination Certificate
2007-07-17
2007-07-17
Nguyen, Ngoc-Yen (Department: 1754)
Chemistry of inorganic compounds
Treating mixture to obtain metal containing compound
Radioactive metal
C423S070000, C423S249000, C423S263000, C210S681000, C210S682000, C210S688000
Reexamination Certificate
active
11408005
ABSTRACT:
Undesirable metal cation contaminants, including hafnium, can be reduced from a solution containing Lutetium-177 on a bed of an anion exchange resin. The thus purified solution can be stored and transported in a polypropylene vial, to prevent the possibility of hafnium entering the solution from a glassware wall and of Lutetium from being lost from the solution by chemically reacting with a glassware wall. The vial can be sealed with a rubber stopper which has a polytetrafluoroethylene coating facing the solution to prevent the possibility of contaminants which could interfere with later uses of the Lutetium-177 from leaching into the solution from the rubber stopper. Recipients of the Lutetium-177-containing vial can be provided with a prepackaged column of the anion exchange resin to enable such recipients to remove the hafnium which accumulated in the solution as a product of radioactive decay during shipment.
REFERENCES:
patent: 5792357 (1998-08-01), Wai et al.
patent: 6162648 (2000-12-01), Maloney et al.
patent: 6716353 (2004-04-01), Mirzadeh et al.
Kumric, K. et al, “Supported liquid membrane extraction of 177Lu(III) with DEHPA and its application for purification of 177Lu-DOTA-Lanerotide”, Separation and Purification Technology 51 (2006), pp. 310-317.
Kleinhanns, I. et al, “Combined Chemical Separation of Lu, Hf, Sm, Nd, and REEs from a Single Rock Digest: Precise and Accurate Isotope Determinations of Lu-Hf and Sm-Nd Using Multicollector-ICPMS”, Anal. Chem. 2002, 74, pp. 67-73.
Camp, Jr. Arthur E.
Hernandez, Jr. Jesse J.
Maloney Thomas J.
Casperson John R
Iso-Tex Diagnostics, Inc.
Nguyen Ngoc-Yen
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