Purification of L-phenylalanine

Details Purification of L-phenylalanine Purification of L-phenylalanine

1984-11-27

1986-04-22

Reamer, James H.

Organic compounds -- part of the class 532-570 series

Organic compounds

Carboxylic acids and salts thereof

C07C 4579

Patent

active

045843996

ABSTRACT:
A process is disclosed for the separation and recovery of L-phenylalanine from an impure aqueous solution by ultrafiltering and/or centrifuging to remove cellular material and large proteins, contacting the filtered solution with activated carbon to adsorb L-phenylalanine, eluting adsorbed L-phenylalanine, passing the eluate through an ion exchanger, and recovering substantially pure L-phenylalanine from the ion exchange eluate.

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patent: 3767528 (1973-10-01), Nagasaki et al.
patent: 3917511 (1975-11-01), Nakayama et al.
Kirk-Othmer, "Encyclopedia of Chem. Tech.", vol. 2, p. 103 (1964).
Jindrich et al., Chem. Abst., vol. 59, #6714g (1960).
Greenstein et al., Chem. of Amino Acids, 1961, 1459.
Samejima, Microbial Prod. of Amino Acids, 1972, 227-59 (CH9).
Neklyudov et al., Khim.-Farm Zh. 1978 (USSR) 12/21-26.
Cogan et al., J. Sci. Food & Agri. 1981, 32/459-66.
Abe et al., Bull. Chem. Soc. Jpn. 1982 (JAPAN) 55/687-89.

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