Purification of immunoglobulin M

Chemistry: natural resins or derivatives; peptides or proteins; – Proteins – i.e. – more than 100 amino acid residues – Blood proteins or globulins – e.g. – proteoglycans – platelet...

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530413, 530808, 530809, 530830, C07K 320, C07K 328, C07K 1500, C07K 1514

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active

050773917

ABSTRACT:
Immunoglobulin M is purified by absorption upon an insoluble matrix material having chemically bound thereon the protein C1q. The matrix is washed and purified immunoglobulin M is then released from the matrix.

REFERENCES:
patent: 4704366 (1987-11-01), Juarez-Salinas et al.
patent: 4882423 (1989-11-01), Taguchi et al.
Svehag, S-E., and D. Burger, (1976), Isolation of C1q Binding Immune Complex . . . , Arch. Phys. Med. Rehabil. 57:45-52.
Casali, P., and P-H. Lambert, (1979), Purification of Soluble . . . , Clin. Exh. Immunol. 37(2):295-309.
Diwan, J. J. et al., (1987), Interaction of Quinine with Mitochondrial K.sup.+ Transport . . . , Adv. Memb. Biochem. Bioenerg., Kim et al. (editors), p. 405.
Gibbons et al., Biochimica et. Biophys. Acta, vol. 670 (1981), pp. 146-149.
Svahag et al., Acta. Path. Microbiol. Scand. Sect. C (1976), vol. 84, pp. 45-52.

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