Chemistry of carbon compounds – Miscellaneous organic carbon compounds – C-metal
Patent
1981-08-18
1983-05-03
Hazel, Blondel
Chemistry of carbon compounds
Miscellaneous organic carbon compounds
C-metal
424 85, A61K 4502, C07G 700
Patent
active
043820271
ABSTRACT:
Disclosed is a process for the purification of crude immune interferon to a near homogeneous preparation which comprises: (a) adsorbing the crude interferon onto a column containing Controlled Pore Glass beads and eluting with ammonium sulfate, (b) adsorbing the interferon containing eluant onto a column containing either Concanavalin A-Sepharose, lentil lectin-Sepharose or pea lectin-agarose and eluting with a buffer containing a sugar, (c) adsorbing the interferon containing eluant onto a column containing Heparin-Sepharose or Procian Red-agarose and eluting with a high salt content buffer, and (d) treating the interferon containing eluant in a gel-filtration column equilibrated in high salt to obtain a solution of immune interferon that is nearly homogeneous.
REFERENCES:
patent: 4168261 (1979-09-01), Edy
patent: 4314935 (1982-02-01), Uemura et al.
Yip, Y., et al., Proc. Natl. Acad. Sci., vol. 78, pp. 1601-1605, 1981.
Chemical Abstract, vol. 93, p. 321, Abst. No. 218752, 1980.
Hazel Blondel
Meloy Laboratories Inc.
LandOfFree
Purification of human immune interferon does not yet have a rating. At this time, there are no reviews or comments for this patent.
If you have personal experience with Purification of human immune interferon, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Purification of human immune interferon will most certainly appreciate the feedback.
Profile ID: LFUS-PAI-O-1208550