Purification of hTNF

Details Purification of hTNF Purification of hTNF

1986-07-18

1988-04-05

Kight, John

Chemistry: natural resins or derivatives; peptides or proteins;

Proteins, i.e., more than 100 amino acid residues

Separation or purification

530412, 530417, 530351, 435803, 435 68, C07K 322

Patent

active

047360208

ABSTRACT:
The purification of hTNF by ion exchange chromatography is described.

REFERENCES:
Yamada et al, CA, vol. 104, #2050322, 1986.
Fiers et al, WPI, abstract to WO86/03751.
Richay, Am. Laboratory, 1982.
Fagenstrom et al, J. Chromato, 206, 1983, pp. 523-532.
Practical Protein Chemistry, 1986, ed. Darbre.
Mariya et al, CA, vol. 105, #207347a, 1986.
Kato et al, CA, vol. 105, #222217b, 1986.
Kato et al, Biochem. Biophys. Res. Comm., 1985, 130, pp. 692-699.
Proc. Nat. Acad. Sci. USA, vol. 72, No. 9, p. 3666 (1975).
Nature, vol. 312, 20/27 Dec. 1984.
Biological Chemistry, 260, 2345 (1985).

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