Liquid purification or separation – Processes – Liquid/liquid solvent or colloidal extraction or diffusing...
Patent
1995-03-20
1996-08-13
therkorn, Ernest G.
Liquid purification or separation
Processes
Liquid/liquid solvent or colloidal extraction or diffusing...
210656, 2101982, 530385, 530413, 530416, 530417, B01D 1508
Patent
active
055453287
ABSTRACT:
A preselected hemoglobin species is separated from contaminants having a different acidity from that of the preselected hemoglobin species, by an overload displacement chromatography process. To remove more acidic contaminants, the process is conducted under anion exchange conditions. To remove more basic contaminants, the process is conducted under cation exchange conditions. In either case, the exchange column is overloaded to displace the hemoglobin species therefrom with contaminants having greater affinity for the column, and using the impure hemoglobin solution as the displacer.
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Ashraf Salman
Magnin Anthony A.
Pliura Diana H.
Wiffen Diane E.
Hemosol Inc.
Therkorn Ernest G.
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