Purification of crude Ioversol using reverse osmosis

Liquid purification or separation – Processes – Liquid/liquid solvent or colloidal extraction or diffusing...

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210652, 210653, B01D 6100

Patent

active

051604370

ABSTRACT:
The use of reverse osmosis as an alternative or substitute method for the purification of a crude diagnostic agent. In the purification process a crude Ioversol solution is contacted with a cross-linked membrane under pressure, forcing the low molecular weight impurities within the crude Ioversol solution through the membrane pores and retaining Ioversol molecules.

REFERENCES:
patent: 4277344 (1981-07-01), Cadotte
patent: 4385046 (1983-05-01), Milbrath et al.
patent: 4396568 (1983-08-01), Lin
patent: 4997983 (1991-03-01), McCarthy
patent: 5019371 (1991-05-01), Lin et al.

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