Chemistry: natural resins or derivatives; peptides or proteins; – Proteins – i.e. – more than 100 amino acid residues – Blood proteins or globulins – e.g. – proteoglycans – platelet...
Patent
1986-09-15
1989-06-20
Schain, Howard E.
Chemistry: natural resins or derivatives; peptides or proteins;
Proteins, i.e., more than 100 amino acid residues
Blood proteins or globulins, e.g., proteoglycans, platelet...
530413, 530417, 530412, 424 858, 435803, C07R 312
Patent
active
048410241
ABSTRACT:
I(g)G3 antibody is purified by affinity chromatography and collection of released antibody at a pH of 9.0 to 9.6. The purification is effected in a column containing both an affinity matrix and a desalting matrix, with the column being equilibrated to a pH of from 9.0 to 9.6. I(g)G3 antibody may be stored at pH 9.0 to 9.6.
REFERENCES:
patent: 4233286 (1980-11-01), Soothill et al.
patent: 4272506 (1981-06-01), Schwarzberg
patent: 4560504 (1985-12-01), Arnold
patent: 4618589 (1986-10-01), Jifferie et al.
patent: 4639513 (1987-01-01), Hou et al.
Nathans Gene R.
Rosenstein Robert W.
Becton Dickinson and Company
Draper Garnette D.
Lillie Raymond J.
Olstein Elliot M.
Schain Howard E.
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