Purification method of crude product

Details Purification method of crude product Purification method of crude product

1995-03-22

1996-08-20

Therkorn, Ernest G.

Liquid purification or separation

Processes

Chromatography

2101982, 426490, 426662, B01D 1508

Patent

active

055475809

ABSTRACT:
Disclosed herein is a purification method of a crude product by column chromatography on silica gel or on a vinyl alcohol copolymer. Methanol-containing n-hexane and/or n-hexane-containing methanol is used as an eluent to elute the crude product, thereby obtaining an intended product with high purity and good yield. The solvents recovered from the effluent can be regenerated without any trouble such as rectification and a great cost by mixing them under stirring and then separating the resulting upper and lower layer from each other. The column used can also be reused again and again by washing with methanol. The separation and purification method is excellent in separation efficiency, operation efficiency and economical efficiency.

REFERENCES:
patent: 4290893 (1981-09-01), Hare
patent: 4353801 (1982-10-01), Mukoyama
patent: 4425276 (1984-01-01), Gunther
patent: 4857236 (1989-08-01), Gunther
patent: 4960762 (1990-10-01), Sellergren
patent: 5015423 (1991-05-01), Eguchi
patent: 5062959 (1991-11-01), Ross
patent: 5169521 (1992-12-01), Oka
Abstract of Japan Pat. No. 1-277457 submitted by applicant on Feb. 16, 1994.
Derwent Abstract of Japan Pat. No. 1-277457 1 page.
Snyder, Introduction to Modern Liquid Chromatography, John Wiley & Sons, New York, 1979, pp. 3, 4, 374-383, & 397-398.
Okamoto, Journal of Chromatography, 588 (1991) pp. 177-180.
Hirata, "Amphipathic Character of Hydrophilic Polymer Gel Columns", Journal of Chromatography, 396(1987) pp. 115-120.
Translation of Japanese Patent Application 277,457 /1989 certified by Fumio Takagi on Jan. 17, 1995, pp. 1-18.

Affiliated with

Also associated with

Rating

Purification method of crude product does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Purification method of crude product, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Purification method of crude product will most certainly appreciate the feedback.

Rate now

Comments { 0 }

Profile ID: LFUS-PAI-O-2328141