Purification and manipulation of bone marrow and blood cells on

Chemistry: molecular biology and microbiology – Measuring or testing process involving enzymes or... – Involving antigen-antibody binding – specific binding protein...

Patent

Rate now

  [ 0.00 ] – not rated yet Voters 0   Comments 0

Details

435 724, 435 2, 436 56, 436172, 436536, G01N 33567, G01N 3353, G01N 3700, A01N 102

Patent

active

058916547

ABSTRACT:
The invention provides methods for purifying or manipulating bone marrow and blood cells based upon P-glycoprotein expression. The methods rely upon immunopurification procedures or upon differential accumulation of materials subject to P-glycoprotein mediated efflux.

REFERENCES:
patent: 5061620 (1991-10-01), Tsukamoto et al.
patent: 5087616 (1992-02-01), Myers
patent: 5464753 (1995-11-01), Chaudhary et al.
Srour, E.F., et al, "Simultaneous Use of CD34, CD15, Anti-HLA-DR and Rhodamine 123 for the Isolation of Precursors of Human Hematopoietic Progenitor Cells", Exp. Hematol. vol. 18, p. 549, Jul. 1990, abstract only.
DAKO bulletin, "The CD System", DAKO Corporation, 1989.
Ploemacher, R.E., et al, "Cells With Marrow and Spleen Repopulating Ability and Forming Spleen Colonies on Day 16, 12, and 8 Are Sequentially Ordered on the Basis of Increasing Rhodamine 123 Retention", Journal of Cellular Physiology, vol. 136, pp. 531-536, 1988.
Neyfakh, A.A, et al, "Multidrug-Resistance Phenotype of a Subpopulation of T-Lymphocytes without Drug Selection", Experimental Cell Research, vol. 185, pp. 496-505, 1989.
Visser et al. (1990) Exp. Hematol 18:248-256.
Sutherland et al. (1990) Proc. Natl. Acad. Sci. USA 87:3584-3588.
Sutherland et al. (1990) Blood 74:1563-1570.
Srour et al. (1990) Exp. Hematol 18:549.
Neyfakh et al. (1988) Exp. Cell Res. 174:168-176.
Neyfakh et al. (1989) Exp. Cell Res. 185:496-505.
McCarthy et al. (1990) I.J. Cell Cloning 8: 184-195.
Spangrude et al. (1990) Proc. Natl. Acad. Sci. USA 87:7433-7437.
Hamada & Tsuruo (1976) Proc. Natl. Acad. Sci. USA 73:7785-7789.
Efferth et al. (1989) "Reciprocal Correlation Between Expression of P-Glycoprotein and Accumulation of Rhodamine 123 in Human Tumors." Anticancer Research 9: 1633-1638.
Ploemacher et al., (1988) "Cells WIth Marrow and Spleen Repopulation Ability and Forming Spleen Colonies on Day 16, 12, and 8 are Sequentially Ordered on the Basisi of Increasing Rhodamine 123 Retention." J. Cell. Cancer. Res. 50: 3167.
Hamada et al., (1990) "Mouse-Human Chimeric Antibody Against the Multidrug Transporter P-Glycorprotein." Cancer Res. 50: 3167.
DAKO bulletin, (1989) "The CD System".
Ball et al. (1990) "Correlation of CD34 and Multidrug Resistance P170 with Fab and Cytogentics but not Prognosis in Acute Myeloid Leukemia (AML)." Blood 76(10, Suppl. 1):225a.
Mulder et al., (1987) "Separation and Functional Analysis of Bone Marrow Cells Seperated by Rhodamine-123 Fluoresence." Exp. Hematol. 15:99-104.
Bertoncell et al. (1985), "Multoparameter Analysis of Transplantable Hempoietic Stem Cells: I. The Separation and Enrichment of Stem Cells Homing to Marrow and Spleen on the Basis of Rhodamine-123 Fluoresence." Exp. Hematol. 13:999-1006.
Van der Bliek et al., (1989) "Multi-Drug Resistance.", Advances in Cancer Research 52:165.
Weide et al., Leukemia, vol. 4, pp. 695-699, Oct. 1990.
van der Bliek et al. Advances in Cancer Research, 52, p. 165, 1989.

LandOfFree

Say what you really think

Search LandOfFree.com for the USA inventors and patents. Rate them and share your experience with other people.

Rating

Purification and manipulation of bone marrow and blood cells on does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Purification and manipulation of bone marrow and blood cells on , we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Purification and manipulation of bone marrow and blood cells on will most certainly appreciate the feedback.

Rate now

     

Profile ID: LFUS-PAI-O-1370203

  Search
All data on this website is collected from public sources. Our data reflects the most accurate information available at the time of publication.