Pure salts of clavulanic acid, e.g. lithium clavulanate

Details Pure salts of clavulanic acid, e.g. lithium clavulanate Pure salts of clavulanic acid, e.g. lithium clavulanate

1978-03-20

1984-12-25

Berch, Mark L.

Chemistry of carbon compounds

Miscellaneous organic carbon compounds

C-metal

424272, C07D49804, A61K 3142

Patent

active

044902948

ABSTRACT:
The invention provides the compound (2R,5R,Z)-3-(2-hydroxyethylidene)-7-oxo-4-oxa-1-azabicyclo-[3,2,0]-heptane -2-carboxylic acid and its salts in purified form and pharmaceutical compositions containing them and a process for the purification of such compounds by conversion in aqueous media to the lithium salt of the above acid and precipitation thereof.

REFERENCES:
Cole et al.-C.A. 84, 72635t (1976)-Abstract of German Offen. 2,517,316 of 10-23-75.

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