Pulverulent mannitol of moderate friability and process for its

Details Pulverulent mannitol of moderate friability and process for its Pulverulent mannitol of moderate friability and process for its

1994-09-26

1996-11-12

Page, Thurman K.

Drug, bio-affecting and body treating compositions

Preparations characterized by special physical form

Food or edible as carrier for pharmaceutical

424489, A61K 914

Patent

active

055737773

ABSTRACT:
The invention relates to a relatively pure pulverulent mannitol, having a moderate and not excessive friability of between 40 and 80% in a Test I, a low apparent density of between 300 and 525 g/l for a particle size cut of between 100 and 200 microns and, additionally, a specific particle size in the sense that it contains less than 30% of particles with a size of less than 75 microns. This pulverulent mannitol possesses remarkable functional properties which make its use particularly recommended as sweetening agent, texturizing agent or additive excipient or vehicle in the food and pharmaceutical industries.

REFERENCES:
patent: 3145146 (1964-08-01), Liebermann
patent: 3341415 (1967-09-01), Scott
patent: 4293570 (1981-10-01), Vadasz
patent: 4661647 (1987-04-01), Serpelloni et al.
patent: 5160680 (1992-11-01), Serpelloni et al.
Jinot et al., Chemical Abstracts, vol. 105, 1987, #48934.

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