Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Carbohydrate doai
Patent
1996-06-03
1998-05-26
Kight, John
Drug, bio-affecting and body treating compositions
Designated organic active ingredient containing
Carbohydrate doai
514 54, 514951, 536103, 424464, 424489, A61K 31715, A61K 914, A61K 920, C08B 3716
Patent
active
057564841
ABSTRACT:
The invention relates to a novel pulverulent hydroxypropyl-.beta.-cyclodextrin compound having a centered particle size free of fine particles and an appreciably improved capacity to dissolve in aqueous medium. The compound also has good flowability and has the advantage of being compressible. The invention also relates to a process for the preparation of this pulverulent hydroxypropyl-.beta.-cyclodextrin compound.
REFERENCES:
patent: 4727064 (1988-02-01), Pitha
patent: 4920214 (1990-04-01), Friedman
patent: 5674854 (1997-10-01), Bodley et al.
patent: 5679660 (1997-10-01), Bodley et al.
Szejtli, J. Medicinal Research Reviews, vol. 14(3), pp. 353-386, (1994).
Uekama et al. CRC Critical Reviews in Therapeutic Drug Carrier Systems, vol. 3(1), pp. 1-40, (1988).
Chemical abstracts, vol. 93, No. 14, 6 Oct. 1980 Columbus, Ohio, US; abstract No. 134246, *abstract* and JP-A-55 056 801.
"New Trends in Cyclodextrins and Derivatives" edited by Prof. Duchene D. in 1991.
Fuertes Patrick
Lis Jose
Serpelloni Michel
Vappereau Bruno
Kight John
Lee Howard C.
Roquette Freres
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