Pulsed cavitational ultrasound therapy

Details Pulsed cavitational ultrasound therapy Pulsed cavitational ultrasound therapy

2008-05-15

2011-11-15

Chen, Tse (Department: 3777)

Surgery: kinesitherapy

Kinesitherapy

Ultrasonic

Reexamination Certificate

active

08057408

ABSTRACT:
Therapy methods using pulsed cavitational ultrasound therapy can include the subprocesses of initiation, maintenance, therapy, and feedback of the histotripsy process, which involves the creation and maintenance of ensembles of microbubbles and the use of feedback in order to optimize the process based on observed spatial-temporal bubble cloud dynamics. The methods provide for the subdivision or erosion of tissue, liquification of tissue, and/or the enhanced delivery of therapeutic agents. Various feedback mechanisms allow variation of ultrasound parameters and provide control over the pulsed cavitational process, permitting the process to be tuned for a number of applications. Such applications can include specific tissue erosion, bulk tissue homogenization, and delivery of therapeutic agents across barriers.

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